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Genomic screening

Comprehensive hereditary cancer panel

One test for the main inherited cancer syndromes: breast, ovarian, bowel, uterine, gastric, pancreatic and more.

What it measures

Breast and ovarian cancer genes (BRCA1, BRCA2, PALB2 and others)Lynch syndrome genes (MLH1, MSH2, MSH6, PMS2, EPCAM)Colorectal, gastric and pancreatic cancer genesEndocrine, kidney and skin cancer genes30 or more genes in total (list published at launch)
This is a screening test, not a diagnosis. Results are explained by a doctor and, where needed, a genetic counsellor. High-probability results are confirmed with diagnostic testing arranged with your doctor.
Where it is tested. Genomic tests are performed by an accredited specialist genomics laboratory, in Australia or overseas. We name the laboratory, its accreditation and where it is on this page before ordering opens, and you consent to that before you order. The laboratory receives your sample and a KnowLuna sample number, never your name or contact details, and destroys the sample and raw sequencing data after reporting.

Who it's for

Women with cancer on both sides of the family, several cancer types in relatives, cancers diagnosed young, or who want one test covering the main inherited cancer syndromes. Adults aged 18 and over.

What you'll learn, and what you won't

A multi-gene panel looks for changes across the genes behind the common hereditary cancer syndromes at once. It finds more than a single-syndrome test, and it also returns more variants of uncertain significance, which is why the result is always explained by a genetic counsellor. A positive result leads to a personal screening plan and to cascade testing for relatives, usually rebated.

A genetic test is one input to a doctor's assessment, not a diagnosis on its own. If anything needs prompt attention a doctor contacts you directly.

How it works

  • Order online. Either use the request your own doctor has signed, or a KnowLuna women's health doctor reviews your details and requests the test.
  • Collect the way that suits you: at a centre near you, with a home kit, or a nurse visit (options below). Saliva kit at home or a blood draw. Any time. Once in a lifetime.
  • Results are ready about 3 to 4 weeks from the sample reaching the laboratory, explained in your account, with a doctor to talk them through and a genetic counsellor where a result calls for it.

Choose how you collect

Every option is the same accredited test and the same report. Pick what suits you at checkout; the fee, if any, is added to either pathway price.

Home kit, swab or salivaIncluded

The kit is posted to you with instructions and a prepaid return satchel. No blood, no appointment. Included.

Collection centreIncluded

A quick draw at an accredited pathology collection centre near you. Usually under ten minutes. Included.

Nurse home visit+$129

A registered nurse comes to your home or workplace for a standard blood draw. Metro areas of capital cities; other locations on request.

Accredited collection centres operate in every state and territory. We show you the closest ones the moment your test is requested.

Common questions

How is this different from the breast and ovarian panel?

It includes those genes and adds the genes behind bowel and uterine cancer (Lynch syndrome), stomach, pancreatic, kidney, skin and endocrine cancers. Choose it where the family history is broader than breast and ovarian cancer, or where you want one test covering the main syndromes.

What is a variant of uncertain significance?

A gene change that has not yet been classified as harmful or harmless. Most are later reclassified as harmless. It is not treated as a positive result, and a genetic counsellor explains it to you.

Know what's happening.
Then decide.
Doctor-requested. Plain English. On your terms.
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